General Cell Lines and Cell Cultures
ATCC SW48 Quantitative; purified DNA, 3 ug; Human
Purified genomic DNA isolated from the SW-48 human colon adenocarcinoma cell line (ATCC CCL-231). This product was quantified for oncology biomarkers EGFR p.G719S via NGS and ddPCR.
ATCC Candida albicans; genomic DNA
Purified genomic DNA (deoxyribonucleic acid), 5 micrograms, dried. Isolated from Candida albicans ATCC 14053 (strain NIH 3172).
W6/32 Hybridoma (Mouse, Mus musculus) - ATCC HB-95
W6/32 is a mouse hybridoma cell line that produces a pan-HLA class I monoclonal antibody reactive with monomorphic determinants on HLA-A, HLA-B, and HLA-C molecules. The antibody is cytotoxic and is commonly used for capture and detection of HLA class I complexes in immunology and immunopeptidomics workflows.
- Cell line derived from mouse (Mus musculus) hybridoma.
- Produces a pan-HLA class I monoclonal antibody reactive with HLA-A, HLA-B, and HLA-C.
- Antibody is IgG2a isotype and exhibits cytotoxic activity.
- Cross-reacts with ape, monkey, and cow cells; no reactivity with rabbit cells.
- Used in immunology and immunopeptidomics applications for capture and detection of HLA class I complexes.
Eurofins Discoverx ChemiScreen CXCR5 Chemokine Receptor Stable Cell Line, 2 vials. (HTS055C)
The ChemiScreen CXCR5 Chemokine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL13/BCA-1/BLC) based activation of CXCR5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Listeria monocytogenes; genomic DNA
Genomic DNA isolated from Listeria monocytogenes strain Li 2 (ATCC 19115). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
ATCC Hs 940.T; Melanoma; Human (Homo sapiens)
Hs 940.T are fibroblasts that were isolated from the skin of a 57-year-old, white male patient with melanoma. It has applications in cancer research.
ATCC Endothelial Cell Growth Kit-VEGF
The Endothelial Cell Growth Kit-VEGF contains components that when added to Vascular Cell Basal Medium (ATCC PCS-100-030) create a complete, low serum culture environment for human large vessel endothelial cells. Use of the Endothelial Cell Growth Kit-VEGF will support a faster rate of proliferation because of the presence of several purified human recombinant (rh) growth factors (rh VEGF, rh EGF, rh FGF basic, and rh IGF-1) combined with heparin and hydrocortisone.
Amsbio LLC Color Switch, CRE report cell line: HEK293-loxP-GFP-RFP Neo)
Color Switch CRE report cell line: HEK293-loxP-GFP-RFP Neo)
Eurofins Discoverx PathHunter VIPR2 Total Internalization U2OS Cell Line, 2 vials. (93-0824C3)
The PathHunter VIPR2 Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of VIPR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged VIPR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the VIPR2 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Lonza Walkersville Human Mesenchymal Stem Cell (hMSC) Chondrogenic Differentiation Medium BulletKit
Stem cells possess the unique ability to differentiate into multiple lineages of cells including chondrocytes. Lonza’s hMSC Chondrogenic Differentiation BulletKit Medium is a serum containing medium designed to induce chondrogenic differentiation, with the addition of TGF-β3, of human bone marrow derived mesenchymal stem cells into mature, functionally active chondrocytes in as few as 14 days. Differentiation can then be validated by a variety of methods including staining with alcian blue or safranin.Partial List of Cells Differentiated with hMSC Chondrogenic Differentiation BulletKit Medium*:Human bone marrow derived stem cellsHuman umbilical cord blood derived stem cellsHuman umbilical cord matrix derived stem cellsC57BL/6 mice bone marrow derived stem cellshuman adipose derived stem cellsHuman hamstring tendon derived stem cellsContent:1 x hMSC Chondrogenic Basal Medium (PT-3925)1 x hMSC Chondrogenic SingleQuot Kit (PT-4121)
